Morphine versus Mexiletine for Treatment of Postamputation Pain
نویسندگان
چکیده
منابع مشابه
Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trial.
BACKGROUND Stump and phantom pains are debilitating sequelae of amputations that are often resistant to treatment. The efficacy of pharmacologic therapies, including opioids and sodium channel blockers, for postamputation pain is uncertain. METHODS The authors conducted a double-blind, randomized, placebo-controlled, crossover study in adult patients with postamputation pain of 6 months or lo...
متن کاملPostamputation pain: epidemiology, mechanisms, and treatment
Postamputation pain (PAP) is highly prevalent after limb amputation but remains an extremely challenging pain condition to treat. A large part of its intractability stems from the myriad pathophysiological mechanisms. A state-of-art understanding of the pathophysiologic basis underlying postamputation phenomena can be broadly categorized in terms of supraspinal, spinal, and peripheral mechanism...
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MANAGEMENT of neuropathic pain is not an easy task, especially after pain is well established. Practitioners choose from a bewildering array of ingredients to create their own menus, based on local taste and local experience, with little literature serving up a gold-standard, prize-winning combination. “Morphine versus Mexiletine for Treatment of Postamputation Pain: A Randomized, Placebo-contr...
متن کاملRegenerative Peripheral Nerve Interfaces for the Treatment of Postamputation Neuroma Pain: A Pilot Study
BACKGROUND Originally designed for prosthetic control, regenerative peripheral nerve interfaces (RPNIs) prevent neuroma formation by providing free muscle grafts as physiological targets for peripheral nerve ingrowth. We report the first series of patients undergoing RPNI implantation for treatment of symptomatic postamputation neuromas. METHODS A retrospective case series of all amputees und...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2008
ISSN: 0003-3022
DOI: 10.1097/aln.0b013e31817f4523